TY - JOUR T1 - Trastuzumab (Herceptin) JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. DO - 10.3174/ajnr.A2619 AU - J.J. Gemmete AU - S.K. Mukherji Y1 - 2011/08/03 UR - http://www.ajnr.org/content/early/2011/08/04/ajnr.A2619.abstract N2 - SUMMARY: Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody. ER -