RT Journal Article SR Electronic T1 Clopidogrel (Plavix) JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A2913 A1 J. Comin A1 D. Kallmes YR 2011 UL http://www.ajnr.org/content/early/2011/12/01/ajnr.A2913.abstract AB SUMMARY: Clopidogrel is an inhibitor of platelet aggregation, indicated for the prevention of ischemic stroke and in-stent thrombosis. However, it has a number of drawbacks, including an increased risk of hemorrhage; a clinical effect that is slow in onset and irreversible; a genetically determined variability in its clinical potency; and interactions with other commonly administered drugs. Abbreviations Act-Metactive metabolite of clopidogrelADPadenosine diphosphateAHAAmerican Hospital AssociationGIgastrointestinalGPIIb/IIIaglycoprotein IIb/IIIaPPIproton pump inhibitorVWFvon Willebrand factor