RT Journal Article SR Electronic T1 Visual Cerebral Microbleed Detection on 7T MR Imaging: Reliability and Effects of Image Processing JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A2960 A1 J. de Bresser A1 M. Brundel A1 M.M. Conijn A1 J.J. van Dillen A1 M.I. Geerlings A1 M.A. Viergever A1 P.R. Luijten A1 G.J. Biessels YR 2012 UL http://www.ajnr.org/content/early/2012/02/16/ajnr.A2960.abstract AB SUMMARY: MR imaging at 7T has a high sensitivity for cerebral microbleed detection. We identified mIP processing conditions with an optimal balance between the number of visually detected microbleeds and the number of sections on 7T MR imaging. Even with optimal mIP processing, the limited size of some of the microbleeds and the susceptibility effects of other adjacent structures were a challenge for visual detection, which led to a modest inter-rater agreement, mainly due to missed microbleeds. Automated lesion-detection techniques may be required to optimally benefit from the increased spatial resolution offered by 7T MR imaging. Abbreviations ICCintraclass correlation coefficientMARSMicrobleed Anatomical Rating ScalemIPminimum intensity projectionSIsimilarity indexSMARTSecond Manifestations of ARTerial disease