PT - JOURNAL ARTICLE AU - H.M. Hussein AU - T. Emiru AU - A.L. Georgiadis AU - A.I. Qureshi TI - Assessment of Platelet Inhibition by Point-of-Care Testing in Neuroendovascular Procedures AID - 10.3174/ajnr.A2963 DP - 2012 Mar 15 TA - American Journal of Neuroradiology 4099 - http://www.ajnr.org/content/early/2012/03/15/ajnr.A2963.short 4100 - http://www.ajnr.org/content/early/2012/03/15/ajnr.A2963.full AB - SUMMARY: Antiplatelet agents are an important component of the preventive strategies currently used in clinical practice to minimize the risk of thromboembolic events during and after endovascular procedures. Because of the variability in the response to antiplatelet agents, measuring the degree of platelet inhibition may help identify and properly treat poor responders. POC testing is defined as diagnostic testing at or near the site of patient care. Knowledge of the specifics of these devices among practicing neurointerventionalists is relatively limited. In this article, the different POC devices available are presented, and their clinical utility in relation to endovascular procedures is discussed. Abbreviations ADPadenosine diphosphateAMPadenosine monophosphateARUaspirin reaction unitBASEbaselineCADPcollagen/ADP test cartridgeCEPIcollagen/epinephrine test cartridgeCIconfidence intervalCITFcollagen-induced thrombus formationGP IIb/IIIaglycoprotein IIb/IIIaLTAlight-transmission aggregometryPARprotease-activated receptorsPAUplatelet aggregation unitsPCIpercutaneous coronary interventionPHTplatelet hemostasis timePOCpoint-of-carePRUP2Y12 reaction units