PT  - JOURNAL ARTICLE
AU  - M A Johnson
AU  - J M Pennock
AU  - G M Bydder
AU  - L M Dubowitz
AU  - D J Thomas
AU  - I R Young
TI  - Serial MR imaging in neonatal cerebral injury.
DP  - 1987 Jan 01
TA  - American Journal of Neuroradiology
PG  - 83--92
VI  - 8
IP  - 1
4099  - http://www.ajnr.org/content/8/1/83.short
4100  - http://www.ajnr.org/content/8/1/83.full
SO  - Am. J. Neuroradiol.1987 Jan 01; 8
AB  - The results of serial MR imaging of the brain in 32 patients with neonatal cerebral injury who had two or more examinations are reviewed. By comparison with normal age-matched controls, delayed or deficient myelination was identified in eight patients on follow-up examination. Developmental delay was present in all of these patients. In three patients delayed myelination was identified at the first study and was normal at follow-up. These patients improved clinically. The most severe delays or deficits in myelination and the most severe handicaps were present in patients with subcortical and periventricular leukomalacia. Ventricular size was readily assessed. Development of porencephalic cysts at sites of previous hemorrhage and infarction was recognized. The lack of ionizing radiation is of particular importance in follow-up MR of children, and an increasing role for this technique in pediatric developmental neurology appears likely.