PT - JOURNAL ARTICLE AU - S. Rawal AU - S.E. Croul AU - R.A. Willinsky AU - M. Tymianski AU - T. Krings TI - Subcortical Cystic Lesions within the Anterior Superior Temporal Gyrus: A Newly Recognized Characteristic Location for Dilated Perivascular Spaces AID - 10.3174/ajnr.A3669 DP - 2013 Aug 14 TA - American Journal of Neuroradiology 4099 - http://www.ajnr.org/content/early/2013/08/14/ajnr.A3669.short 4100 - http://www.ajnr.org/content/early/2013/08/14/ajnr.A3669.full AB - SUMMARY: Cystic parenchymal lesions may pose an important diagnostic challenge, particularly when encountered in unexpected locations. Dilated perivascular spaces, which may mimic cystic neoplasms, are known to occur in the inferior basal ganglia and mesencephalothalamic regions; a focal preference within the subcortical white matter has not been reported. This series describes 15 cases of patients with cystic lesions within the subcortical white matter of the anterior superior temporal lobe, which followed a CSF signal; were located adjacent to a subarachnoid space; demonstrated variable surrounding signal change; and, in those that were followed up, showed stability. Pathology study results obtained in 1 patient demonstrated chronic gliosis surrounding innumerable dilated perivascular spaces. These findings suggest that dilated perivascular spaces may exhibit a regional preference for the subcortical white matter of the anterior superior temporal lobe. Other features—lack of clinical symptoms, proximity to the subarachnoid space, identification of an adjacent vessel, and stability with time—may help in confidently making the prospective diagnosis of a dilated perivascular space, thereby preventing unnecessary invasive management. Abbreviations SASsubarachnoid space