RT Journal Article
SR Electronic
T1 Radiation Dose Reduction in Paranasal Sinus CT Using Model-Based Iterative Reconstruction
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A3749
A1 J.M. Hoxworth
A1 D. Lal
A1 G.P. Fletcher
A1 A.C. Patel
A1 M. He
A1 R.G. Paden
A1 A.K. Hara
YR 2013
UL http://www.ajnr.org/content/early/2013/10/10/ajnr.A3749.abstract
AB BACKGROUND AND PURPOSE: CT performed with Veo model-based iterative reconstruction has shown the potential for radiation-dose reduction. This study sought to determine whether Veo could reduce noise and improve the image quality of low-dose sinus CT. MATERIALS AND METHODS: Twenty patients consented to participate and underwent low- and standard-dose sinus CT on the same day. Standard-dose CT was created with filtered back-projection (120 kV[peak], 210 mA, 0.4-second rotation, and 0.531 pitch). For low-dose CT, mA was decreased to 20 (the remaining parameters were unchanged), and images were generated with filtered back-projection and Veo. Standard- and low-dose datasets were reconstructed by using bone and soft-tissue algorithms, while the low-dose Veo reconstruction only had a standard kernel. Two blinded neuroradiologists independently evaluated the image quality of multiple osseous and soft-tissue craniofacial structures. Image noise was measured by using multiple regions of interest. RESULTS: Eight women and 12 men (mean age, 63.3 years) participated. Volume CT dose indices were 2.9 mGy (low dose) and 31.6 mGy (standard dose), and mean dose-length products were 37.4 mGy-cm (low dose) and 406.1 mGy-cm (standard dose). Of all the imaging series, low-dose Veo demonstrated the least noise (P < .001). Compared with filtered back-projection low-dose CT using soft-tissue and bone algorithms, Veo had the best soft-tissue image quality but the poorest bone image quality (P < .001). CONCLUSIONS: Veo significantly reduces noise in low-dose sinus CT. Although this reduction improves soft-tissue evaluation, thin bone becomes less distinct. Abbreviations BONE FBP LDbone algorithm, filtered back-projection, low doseBONE FBP SDbone algorithm, filtered back-projection, standard doseIRISiterative reconstruction in image spaceSAFIREsinogram-affirmed iterative reconstructionSOFT FBP LDsoft-tissue algorithm, filtered back-projection, low doseSOFT FBP SDsoft-tissue algorithm, filtered back-projection, standard doseVEO LDVeo model-based iterative reconstruction, low dose