RT Journal Article SR Electronic T1 Reversible Cerebral Vasoconstriction Syndrome, Part 1: Epidemiology, Pathogenesis, and Clinical Course JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology DO 10.3174/ajnr.A4214 A1 T.R. Miller A1 R. Shivashankar A1 M. Mossa-Basha A1 D. Gandhi YR 2015 UL http://www.ajnr.org/content/early/2015/01/15/ajnr.A4214.abstract AB SUMMARY: Reversible cerebral vasoconstriction syndrome is a clinical and radiologic syndrome that represents a common presentation of a diverse group of disorders. The syndrome is characterized by thunderclap headache and reversible vasoconstriction of cerebral arteries, which can either be spontaneous or related to an exogenous trigger. The pathophysiology of reversible cerebral vasoconstriction syndrome is unknown, though alterations in cerebral vascular tone are thought to be a key underlying mechanism. The syndrome typically follows a benign course; however, reversible cerebral vasoconstriction syndrome may result in permanent disability or death in a small minority of patients secondary to complications such as ischemic stroke or intracranial hemorrhage. Abbreviations RCVSreversible cerebral vasoconstriction syndromePRESposterior reversible encephalopathy syndrome