@article {Alexander, author = {M.D. Alexander and D.L. Cooke and J. Nelson and D.E. Guo and C.F. Dowd and R.T. Higashida and V.V. Halbach and M.T. Lawton and H. Kim and S.W. Hetts}, title = {Association between Venous Angioarchitectural Features of Sporadic Brain Arteriovenous Malformations and Intracranial Hemorrhage}, year = {2015}, doi = {10.3174/ajnr.A4224}, publisher = {American Journal of Neuroradiology}, abstract = {BACKGROUND AND PURPOSE: Intracranial hemorrhage is the most serious outcome for brain arteriovenous malformations. This study examines associations between venous characteristics of these lesions and intracranial hemorrhage. MATERIALS AND METHODS: Statistical analysis was performed on a prospectively maintained data base of brain AVMs evaluated at an academic medical center. DSA, CT, and MR imaging studies were evaluated to classify lesion side, drainage pattern, venous stenosis, number of draining veins, venous ectasia, and venous reflux. Logistic regression analyses were performed to identify the association of these angiographic features with intracranial hemorrhage of any age at initial presentation. RESULTS: Exclusively deep drainage (OR, 3.42; 95\% CI, 1.87{\textendash}6.26; P \< .001) and a single draining vein (OR, 1.98; 95\% CI, 1.26{\textendash}3.08; P = .002) were associated with hemorrhage, whereas venous ectasia (OR, 0.52; 95\% CI, 0.34{\textendash}0.78; P = .002) was inversely associated with hemorrhage. CONCLUSIONS: Analysis of venous characteristics of brain AVMs may help determine their prognosis and thereby identify lesions most appropriate for treatment.}, issn = {0195-6108}, URL = {https://www.ajnr.org/content/early/2015/01/29/ajnr.A4224}, eprint = {https://www.ajnr.org/content/early/2015/01/29/ajnr.A4224.full.pdf}, journal = {American Journal of Neuroradiology} }