RT Journal Article
SR Electronic
T1 Choroid Plexus Neoplasms: Toward a Distinction between Carcinoma and Papilloma Using Arterial Spin-Labeling
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A4332
A1 V. Dangouloff-Ros
A1 D. Grevent
A1 M. Pagès
A1 T. Blauwblomme
A1 R. Calmon
A1 C. Elie
A1 S. Puget
A1 C. Sainte-Rose
A1 F. Brunelle
A1 P. Varlet
A1 N. Boddaert
YR 2015
UL http://www.ajnr.org/content/early/2015/05/28/ajnr.A4332.abstract
AB SUMMARY: Pediatric choroid plexus papillomas and carcinomas are highly vascularized neoplasms, which are difficult to distinguish with conventional imaging. We aimed to analyze the diagnostic accuracy of PWI, by using both pseudocontinuous arterial spin-labeling and DSC-PWI. We reviewed the PWI of 13 children with choroid plexus neoplasms (7 papillomas and 6 carcinomas). We quantified CBF, relative CBF, and relative CBV in each lesion and compared papillomas and carcinomas. Relative CBF values by using arterial spin-labeling were significantly higher for carcinomas (P = .028). The median value of relative CBF was 1.7 (range, 1.4–1.9) for carcinomas and 0.4 (range, 0.3–0.6) for papillomas. The CBF median value was 115 mL/min/100 g (range, 90–140 mL/min/100 g) for carcinomas and 41 mL/min/100 g (range, 10–73 mL/min/100 g) for papillomas (P = .056). Measures with DSC-PWI were more variable and not significantly different (P = .393). Arterial spin-labeling is a promising technique to differentiate choroid plexus carcinomas and papillomas.AbbreviationsASLarterial spin-labelingrCBFrelative CBFrCBVrelative CBV