TY - JOUR T1 - Diagnostic Quality of 3D T2-SPACE Compared with T2-FSE in the Evaluation of Cervical Spine MRI Anatomy JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 846 LP - 850 DO - 10.3174/ajnr.A5080 VL - 38 IS - 4 AU - F.H. Chokshi AU - G. Sadigh AU - W. Carpenter AU - J.W. Allen Y1 - 2017/04/01 UR - http://www.ajnr.org/content/38/4/846.abstract N2 - BACKGROUND AND PURPOSE: Spinal anatomy has been variably investigated using 3D MRI. We aimed to compare the diagnostic quality of T2 sampling perfection with application-optimized contrasts by using flip angle evolution (SPACE) with T2-FSE sequences for visualization of cervical spine anatomy. We predicted that T2-SPACE will be equivalent or superior to T2-FSE for visibility of anatomic structures.MATERIALS AND METHODS: Adult patients undergoing cervical spine MR imaging with both T2-SPACE and T2-FSE sequences for radiculopathy or myelopathy between September 2014 and February 2015 were included. Two blinded subspecialty-trained radiologists independently assessed the visibility of 12 anatomic structures by using a 5-point scale and assessed CSF pulsation artifact by using a 4-point scale. Sagittal images and 6 axial levels from C2–T1 on T2-FSE were reviewed; 2 weeks later and after randomization, T2-SPACE was evaluated. Diagnostic quality for each structure and CSF pulsation artifact visibility on both sequences were compared by using a paired t test. Interobserver agreement was calculated (κ).RESULTS: Forty-five patients were included (mean age, 57 years; 40% male). The average visibility scores for intervertebral disc signal, neural foramina, ligamentum flavum, ventral rootlets, and dorsal rootlets were higher for T2-SPACE compared with T2-FSE for both reviewers (P < .001). Average scores for remaining structures were either not statistically different or the superiority of one sequence was discordant between reviewers. T2-SPACE showed less degree of CSF flow artifact (P < .001). Interobserver variability ranged between −0.02–0.20 for T2-SPACE and −0.02–0.30 for T2-FSE (slight to fair agreement).CONCLUSIONS: T2-SPACE may be equivalent or superior to T2-FSE for the evaluation of cervical spine anatomic structures, and T2-SPACE shows a lower degree of CSF pulsation artifact.C-spinecervical spineSPACEsampling perfection with application-optimized contrasts by using flip angle evolution ER -