RT Journal Article
SR Electronic
T1 Prospective cerebral MR study of HIV seropositive and seronegative men: correlation of MR findings with neurologic, neuropsychologic, and cerebrospinal fluid analysis.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1231
OP 1240
VO 13
IS 4
A1 Cohen, W A
A1 Maravilla, K R
A1 Gerlach, R
A1 Claypoole, K
A1 Collier, A C
A1 Marra, C
A1 Maxwell, C
A1 Coombs, R W
A1 Longstreth, W T
A1 Townes, B D
YR 1992
UL http://www.ajnr.org/content/13/4/1231.abstract
AB PURPOSE As part of a longitudinal study of human immunodeficiency virus type 1 (HIV) infection, we attempted to identify early cerebral MR findings that might correlate to clinical evidence of central nervous system involvement.METHODS We studied 65 seropositive and 40 seronegative homosexual males using cranial MR, neurologic, immunologic, and neuropsychologic examinations.RESULTS The incidence of mildly enlarged ventricles, sulci, and punctate areas of abnormal signal in both groups was similar in both groups. Diffuse, poorly defined areas of abnormal white matter signal were difficult to consistently identify in seropositives. Enlarged adenoidal lymphoid tissue was found in 30 (46%) of seropositives and 2 (5%) of seronegatives (P = .0001). The incidence of sinus inflammatory change was similar in the two groups.CONCLUSION MR of intracranial contents is substantially normal in a non-AIDS HIV(+) population.