RT Journal Article SR Electronic T1 Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A New “Leave Me Alone” Lesion with a Characteristic Imaging Pattern JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1899 OP 1904 DO 10.3174/ajnr.A5281 VO 38 IS 10 A1 R.H. Nunes A1 C.C. Hsu A1 A.J. da Rocha A1 L.L.F. do Amaral A1 L.F.S. Godoy A1 T.W. Watkins A1 V.H. Marussi A1 M. Warmuth-Metz A1 H.C. Alves A1 F.G. Goncalves A1 B.K. Kleinschmidt-DeMasters A1 A.G. Osborn YR 2017 UL http://www.ajnr.org/content/38/10/1899.abstract AB SUMMARY: Multinodular and vacuolating neuronal tumor of the cerebrum is a recently reported benign, mixed glial neuronal lesion that is included in the 2016 updated World Health Organization classification of brain neoplasms as a unique cytoarchitectural pattern of gangliocytoma. We report 33 cases of presumed multinodular and vacuolating neuronal tumor of the cerebrum that exhibit a remarkably similar pattern of imaging findings consisting of a subcortical cluster of nodular lesions located on the inner surface of an otherwise normal-appearing cortex, principally within the deep cortical ribbon and superficial subcortical white matter, which is hyperintense on FLAIR. Only 4 of our cases are biopsy-proven because most were asymptomatic and incidentally discovered. The remaining were followed for a minimum of 24 months (mean, 3 years) without interval change. We demonstrate that these are benign, nonaggressive lesions that do not require biopsy in asymptomatic patients and behave more like a malformative process than a true neoplasm.DNETdysembryoplastic neuroepithelial tumorMVNTmultinodular and vacuolating neuronal tumor of the cerebrum