TY - JOUR T1 - Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A New “Leave Me Alone” Lesion with a Characteristic Imaging Pattern JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1899 LP - 1904 DO - 10.3174/ajnr.A5281 VL - 38 IS - 10 AU - R.H. Nunes AU - C.C. Hsu AU - A.J. da Rocha AU - L.L.F. do Amaral AU - L.F.S. Godoy AU - T.W. Watkins AU - V.H. Marussi AU - M. Warmuth-Metz AU - H.C. Alves AU - F.G. Goncalves AU - B.K. Kleinschmidt-DeMasters AU - A.G. Osborn Y1 - 2017/10/01 UR - http://www.ajnr.org/content/38/10/1899.abstract N2 - SUMMARY: Multinodular and vacuolating neuronal tumor of the cerebrum is a recently reported benign, mixed glial neuronal lesion that is included in the 2016 updated World Health Organization classification of brain neoplasms as a unique cytoarchitectural pattern of gangliocytoma. We report 33 cases of presumed multinodular and vacuolating neuronal tumor of the cerebrum that exhibit a remarkably similar pattern of imaging findings consisting of a subcortical cluster of nodular lesions located on the inner surface of an otherwise normal-appearing cortex, principally within the deep cortical ribbon and superficial subcortical white matter, which is hyperintense on FLAIR. Only 4 of our cases are biopsy-proven because most were asymptomatic and incidentally discovered. The remaining were followed for a minimum of 24 months (mean, 3 years) without interval change. We demonstrate that these are benign, nonaggressive lesions that do not require biopsy in asymptomatic patients and behave more like a malformative process than a true neoplasm.DNETdysembryoplastic neuroepithelial tumorMVNTmultinodular and vacuolating neuronal tumor of the cerebrum ER -