RT Journal Article
SR Electronic
T1 Resting-State Functional MRI: Everything That Nonexperts Have Always Wanted to Know
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A5527
A1 H. Lv
A1 Z. Wang
A1 E. Tong
A1 L.M. Williams
A1 G. Zaharchuk
A1 M. Zeineh
A1 A.N. Goldstein-Piekarski
A1 T.M. Ball
A1 C. Liao
A1 M. Wintermark
YR 2018
UL http://www.ajnr.org/content/early/2018/01/18/ajnr.A5527.abstract
AB SUMMARY: Resting-state fMRI was first described by Biswal et al in 1995 and has since then been widely used in both healthy subjects and patients with various neurologic, neurosurgical, and psychiatric disorders. As opposed to paradigm- or task-based functional MR imaging, resting-state fMRI does not require subjects to perform any specific task. The low-frequency oscillations of the resting-state fMRI signal have been shown to relate to the spontaneous neural activity. There are many ways to analyze resting-state fMRI data. In this review article, we will briefly describe a few of these and highlight the advantages and limitations of each. This description is to facilitate the adoption and use of resting-state fMRI in the clinical setting, helping neuroradiologists become familiar with these techniques and applying them for the care of patients with neurologic and psychiatric diseases.ALFFAmplitude of Low Frequency FluctuationsBOLDblood oxygen level–dependentFCDfunctional connectivity densityICAindependent component analysisReHoregional homogeneityrs-fMRIresting-state fMRI