PT  - JOURNAL ARTICLE
AU  - H Tice
AU  - P D Barnes
AU  - L Goumnerova
AU  - R M Scott
AU  - N J Tarbell
TI  - Pediatric and adolescent oligodendrogliomas.
DP  - 1993 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1293--1300
VI  - 14
IP  - 6
4099  - http://www.ajnr.org/content/14/6/1293.short
4100  - http://www.ajnr.org/content/14/6/1293.full
SO  - Am. J. Neuroradiol.1993 Nov 01; 14
AB  - PURPOSE To review the clinical and imaging findings in pediatric and adolescent intracranial pure oligodendrogliomas.METHODS The clinical, CT, and MR data in 39 surgically proved pure oligodendrogliomas were retrospectively reviewed.RESULTS The frontal or temporal lobes were involved in 32 (82%) cases. Seventy percent of the tumors were hypodense on CT, three-fourths were hypointense on T1-weighted images, and all were hyperintense on spin-density and T2-weighted images. Fewer than 40% of the lesions demonstrated calcification, and nearly 60% had well-defined margins. Mass effect was seen in fewer than half of the cases, and edema could be separately identified in only one case. Tumor enhancement was seen in fewer than 25%. In 39 cases after partial (3), subtotal (16), or total (20) resection, follow-up studies demonstrated stability over a mean period of 5 years.CONCLUSION The findings in this pediatric series of pure oligodendrogliomas (without mixed cell elements) differ from previous adult series in that calcification, contrast enhancement, and edema are seen less frequently. In addition, very slow or no growth is often characteristic, and these patients have an excellent prognosis with surgical resection.