PT  - JOURNAL ARTICLE
AU  - C DeCarli
AU  - D G Murphy
AU  - J A Gillette
AU  - J V Haxby
AU  - D Teichberg
AU  - M B Schapiro
AU  - B Horwitz
TI  - Lack of age-related differences in temporal lobe volume of very healthy adults.
DP  - 1994 Apr 01
TA  - American Journal of Neuroradiology
PG  - 689--696
VI  - 15
IP  - 4
4099  - http://www.ajnr.org/content/15/4/689.short
4100  - http://www.ajnr.org/content/15/4/689.full
SO  - Am. J. Neuroradiol.1994 Apr 01; 15
AB  - PURPOSE To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age. METHODS MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions. RESULTS There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age. CONCLUSION In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life.