RT Journal Article
SR Electronic
T1 Characteristics of ethylene vinyl alcohol copolymer (EVAL) mixtures.
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1103
OP 1105
VO 15
IS 6
A1 K Yamashita
A1 W Taki
A1 H Iwata
A1 I Nakahara
A1 S Nishi
A1 A Sadato
A1 K Matsumoto
A1 H Kikuchi
YR 1994
UL http://www.ajnr.org/content/15/6/1103.abstract
AB PURPOSE To determine physical characteristics of mixtures of ethylene vinyl alcohol copolymer (EVAL) and metrizamide dissolved in dimethyl sulfoxide, liquid materials developed for embolization of arteriovenous malformations. METHODS EVAL and dimethyl sulfoxide were mixed in various proportions and sterilized. The viscosity and density of each mixture was measured. Precipitation times were determined by dropping the mixtures into saline or human blood. The mixtures were filtered and the filtrates weighed. RESULTS Densities and viscosities of the various mixtures differed significantly, proportionally to the concentration of EVAL. Precipitation times also differed significantly, in inverse proportion to the concentration of EVAL. Temperature and aqueous solution did not affect precipitation times significantly. The weight of the filtrate significantly increased with time but was constant for each precipitation time. Temperature significantly affected filtrate weight; aqueous solution did not. CONCLUSIONS Because of their different physical properties, the various EVAL mixtures are suited to embolizing different types of arteriovenous malformations.