TY - JOUR T1 - MR of intracranial tumors: combined use of gadolinium and magnetization transfer. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1727 LP - 1736 VL - 15 IS - 9 AU - T Kurki AU - P Niemi AU - S Valtonen Y1 - 1994/10/01 UR - http://www.ajnr.org/content/15/9/1727.abstract N2 - PURPOSE To study the potential combined application of gadolinium and magnetization transfer in the MR imaging of intracranial tumors. METHODS Twenty-two patients were imaged at low field strength (0.1 T). Corresponding gradient-echo partial saturation images without and with magnetization transfer pulse were produced. Images with intermediate repetition times were obtained in 18 cases; five different sequences were produced in 4 cases. Gadopentetate dimeglumine was used at a dose of 0.1 mmol/kg. RESULTS Magnetization transfer effect increased the contrast between enhancing lesion and normal brain and the contrast between edema and normal brain; the contrast between enhancing lesion and edema was not significantly changed. On intermediate-repetition-time magnetization transfer images the contrast between enhancing tumor and normal brain and the contrast between edema and normal brain were superior to short-repetition-time magnetization transfer images, but the differentiation between enhancing tumor and edema was poorer. CONCLUSION Magnetization transfer can be used to improve contrast in Gd-enhanced MR imaging. Combining magnetization transfer with an intermediate-repetition-time image provides the possibility for displaying both enhancing and nonenhancing lesions on a single MR image. ER -