RT Journal Article
SR Electronic
T1 Vessel Wall MRI for Targeting Biopsies of Intracranial Vasculitis
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A5801
A1 S.R. Zeiler
A1 Y. Qiao
A1 C.A. Pardo
A1 M. Lim
A1 B.A. Wasserman
YR 2018
UL http://www.ajnr.org/content/early/2018/09/27/ajnr.A5801.abstract
AB SUMMARY: Central nervous system vasculitides are elusive diseases that are challenging to diagnose because brain biopsies have high false-negative rates. We sought to test the ability of contrast-enhanced, high-resolution 3D vessel wall MR imaging to identify vascular inflammation and direct open biopsies of intracranial target vessels and adjacent brain parenchyma. Eight of 9 specimens revealed vascular inflammation. We conclude that vessel wall MR imaging can identify inflamed intracranial vessels, enabling precise localization of biopsy targets.CNSVCNS vasculitisVWMRIvessel wall MR imaging