PT  - JOURNAL ARTICLE
AU  - A Falini
AU  - A J Barkovich
AU  - G Calabrese
AU  - D Origgi
AU  - F Triulzi
AU  - G Scotti
TI  - Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study.
DP  - 1998 Apr 01
TA  - American Journal of Neuroradiology
PG  - 648--652
VI  - 19
IP  - 4
4099  - http://www.ajnr.org/content/19/4/648.short
4100  - http://www.ajnr.org/content/19/4/648.full
SO  - Am. J. Neuroradiol.1998 Apr 01; 19
AB  - The findings at sequential MR imaging and proton MR spectroscopy of a patient with profound hypoxic-ischemic brain injury are reported. The pattern of structural and biochemical changes observed closely reflected the known evolution of postasphyxic brain degeneration. Particularly noteworthy were the sharp decrease of cortical N-acetylaspartate in the acute phase, suggesting the severity of the neuronal insult, and the subsequent progressive increase of choline, paralleling the delayed degeneration of white matter.