PT  - JOURNAL ARTICLE
AU  - R E Whitehead
AU  - C B MacDonald
AU  - E R Melhem
AU  - L McMahon
TI  - Spontaneous labyrinthine hemorrhage in sickle cell disease.
DP  - 1998 Sep 01
TA  - American Journal of Neuroradiology
PG  - 1437--1440
VI  - 19
IP  - 8
4099  - http://www.ajnr.org/content/19/8/1437.short
4100  - http://www.ajnr.org/content/19/8/1437.full
SO  - Am. J. Neuroradiol.1998 Sep 01; 19
AB  - We report the clinical and MR imaging findings in two African-American patients with manifestations of sickle cell disease affecting the inner ear. Both suffered sudden-onset sensorineural hearing loss and vestibular symptoms, and both had high labyrinthine signal on T1-weighted MR images attributed to labyrinthine hemorrhage. Follow-up studies of the first patient revealed a decrease in abnormal vestibular signal. Careful attention to the labyrinth on T1-weighted MR images can reveal vestibulocochlear clinical findings in sickle cell patients, with important implications for management and prognosis.