TY - JOUR T1 - Ophthalmoplegic migraine: reversible enhancement and thickening of the cisternal segment of the oculomotor nerve on contrast-enhanced MR images. JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 1887 LP - 1891 VL - 19 IS - 10 AU - A S Mark AU - J Casselman AU - D Brown AU - J Sanchez AU - M Kolsky AU - T C Larsen, 3rd AU - P Lavin AU - B Ferraraccio Y1 - 1998/11/01 UR - http://www.ajnr.org/content/19/10/1887.abstract N2 - BACKGROUND AND PURPOSE Ophthalmoplegic migraine is a rare condition characterized by the association of headaches and an oculomotor nerve palsy. We report six patients with typical clinical features of this disorder in whom enhancement of the cisternal segment of the oculomotor nerve developed during the acute phase, followed by resolution of enhancement over several weeks as the symptoms resolved.METHODS Six patients, ages 3 to 27 years, underwent MR imaging during the acute phase of ophthalmoplegic migraine and at the time of recovery several weeks later. The MR studies, performed on a 1.5-T MR unit, included noncontrast and contrast-enhanced axial and coronal T1-weighted sequences. Sagittal images were obtained in two patients, with and without contrast enhancement.RESULTS Enhancement of the cisternal segment of the oculomotor nerve was seen in all patients at initial presentation. Contrast-enhanced studies also showed focal thickening at the exit of the nerve in the interpeduncular cistern in five of six patients. No patient had enhancement of the cavernous sinus or adjacent dura. Enhancement was almost completely resolved on follow-up studies 7 to 9 weeks later.CONCLUSION Our findings confirm an intrinsic transient abnormality in the cisternal segment of the third nerve in patients with a typical clinical presentation of ophthalmoplegic migraine. ER -