PT  - JOURNAL ARTICLE
AU  - S.I. Usiskin
AU  - A. Bainbridge
AU  - R.F. Miller
AU  - H.R. Jäger
TI  - Progressive Multifocal Leukoencephalopathy: Serial High-b-Value Diffusion-Weighted MR Imaging and Apparent Diffusion Coefficient Measurements to Assess Response to Highly Active Antiretroviral Therapy
DP  - 2007 Feb 01
TA  - American Journal of Neuroradiology
PG  - 285--286
VI  - 28
IP  - 2
4099  - http://www.ajnr.org/content/28/2/285.short
4100  - http://www.ajnr.org/content/28/2/285.full
SO  - Am. J. Neuroradiol.2007 Feb 01; 28
AB  - SUMMARY: A patient with human immunodeficiency virus–related posterior fossa progressive multifocal leukoencephalopathy had serial diffusion-weighted imaging using b-values of 1000 and 3000 before and during highly active antiretroviral therapy (HAART). High-b-value images provided a superior definition of the leading edge of the lesion and additional information about the integrity of white matter tracts. Following HAART, there was a marked reduction of lesional apparent diffusion coefficient and reconstitution of anisotropy in the affected middle cerebellar peduncle.