RT Journal Article
SR Electronic
T1 A Review of Magnetic Particle Imaging and Perspectives on Neuroimaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A5896
A1 L.C. Wu
A1 Y. Zhang
A1 G. Steinberg
A1 H. Qu
A1 S. Huang
A1 M. Cheng
A1 T. Bliss
A1 F. Du
A1 J. Rao
A1 G. Song
A1 L. Pisani
A1 T. Doyle
A1 S. Conolly
A1 K. Krishnan
A1 G. Grant
A1 M. Wintermark
YR 2019
UL http://www.ajnr.org/content/early/2019/01/14/ajnr.A5896.abstract
AB SUMMARY: Magnetic particle imaging is an emerging tomographic technique with the potential for simultaneous high-resolution, high-sensitivity, and real-time imaging. Magnetic particle imaging is based on the unique behavior of superparamagnetic iron oxide nanoparticles modeled by the Langevin theory, with the ability to track and quantify nanoparticle concentrations without tissue background noise. It is a promising new imaging technique for multiple applications, including vascular and perfusion imaging, oncology imaging, cell tracking, inflammation imaging, and trauma imaging. In particular, many neuroimaging applications may be enabled and enhanced with magnetic particle imaging. In this review, we will provide an overview of magnetic particle imaging principles and implementation, current applications, promising neuroimaging applications, and practical considerations.FFLfield-free lineFFPfield-free pointFFRfield-free regionMPImagnetic particle imagingSPIOsuperparamagnetic iron oxideSPIONsuperparamagnetic iron oxide nanoparticle