RT Journal Article
SR Electronic
T1 Quantitative Susceptibility Mapping to Assess Cerebral Vascular Compliance
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 460
OP 463
DO 10.3174/ajnr.A5933
VO 40
IS 3
A1 C. Birkl
A1 C. Langkammer
A1 P. Sati
A1 C. Enzinger
A1 F. Fazekas
A1 S. Ropele
YR 2019
UL http://www.ajnr.org/content/40/3/460.abstract
AB SUMMARY: This study explored whether autoregulatory shifts in cerebral blood volume induce susceptibility changes large enough to be depicted by quantitative susceptibility mapping. Eight healthy subjects underwent fast quantitative susceptibility mapping at 3T while lying down to slowly decrease mean arterial pressure. A linear relationship between mean arterial pressure and susceptibility was observed in cortical and subcortical structures, likely representing vessels involved in autoregulation. The slope of this relationship is assumed to indicate the extent of cerebral vascular compliance.CVCcerebral vascular compliancegreEPIgradient-echo echo-planar imagingMAPmean arterial blood pressureQSMquantitative susceptibility mappingSpO2peripheral capillary oxygen saturation