TY - JOUR T1 - Comparison of Iterative Model Reconstruction versus Filtered Back-Projection in Pediatric Emergency Head CT: Dose, Image Quality and Image-Reconstruction Times JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. DO - 10.3174/ajnr.A6034 AU - R.N. Southard AU - D.M.E. Bardo AU - M.H. Temkit AU - M.A. Thorkelson AU - R.A. Augustyn AU - C.A. Martinot Y1 - 2019/04/11 UR - http://www.ajnr.org/content/early/2019/04/11/ajnr.A6034.abstract N2 - BACKGROUND AND PURPOSE: Noncontrast CT of the head is the initial imaging test for traumatic brain injury, stroke, or suspected nonaccidental trauma. Low-dose head CT protocols using filtered back-projection are susceptible to increased noise and decreased image quality. Iterative reconstruction noise suppression allows the use of lower-dose techniques with maintained image quality. We review our experience with children undergoing emergency head CT examinations reconstructed using knowledge-based iterative model reconstruction versus standard filtered back-projection, comparing reconstruction times, radiation dose, and objective and subjective image quality.MATERIALS AND METHODS: This was a retrospective study comparing 173 children scanned using standard age-based noncontrast head CT protocols reconstructed with filtered back-projection with 190 children scanned using low-dose protocols reconstructed with iterative model reconstruction. ROIs placed on the frontal white matter and thalamus yielded signal-to-noise and contrast-to-noise ratios. Volume CT dose index and study reconstruction times were recorded. Random subgroups of patients were selected for subjective image-quality review.RESULTS: The volume CT dose index was significantly reduced in studies reconstructed with iterative model reconstruction compared with filtered back-projection, (mean, 24.4 ± 3.1 mGy versus 31.1 ± 6.0 mGy, P < .001), while the SNR and contrast-to-noise ratios improved 2-fold (P < .001). Radiologists graded iterative model reconstruction images as superior to filtered back-projection images for gray-white matter differentiation and anatomic detail (P < .001). The average reconstruction time of the filtered back-projection studies was 101 seconds, and with iterative model reconstruction, it was 147 seconds (P < .001), without a practical effect on work flow.CONCLUSIONS: In children referred for emergency noncontrast head CT, optimized low-dose protocols with iterative model reconstruction allowed us to significantly reduce the relative dose, on average, 22% compared with filtered back-projection, with significantly improved objective and subjective image quality.ASIRadaptive statistical iterative reconstructionCNRcontrast-to-noise ratioCTDIvolvolume CT dose indexFBPfiltered back-projectionIMRiterative model reconstructionMBIRmodel-based iterative reconstructionIRiterative reconstruction ER -