TY - JOUR T1 - Chimeric Antigen Receptor T-Cell Therapy: What the Neuroradiologist Needs to Know JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. DO - 10.3174/ajnr.A6042 AU - H.A. Valand AU - F. Huda AU - R.K. Tu Y1 - 2019/05/02 UR - http://www.ajnr.org/content/early/2019/04/25/ajnr.A6042.abstract N2 - SUMMARY: Chimeric antigen receptor T-cell therapy is an exciting and rapidly emerging “fifth pillar” treatment for hematologic cancers. Unique treatment-related toxicities and cost remain a major hindrance to its widespread application. The commonly faced challenges with this innovative therapy, its neurotoxicity, and manifestation on neuroimaging studies, are reviewed.CARchimeric antigen receptorCRScytokine release syndromeCRESCAR-T-cell–related encephalopathy syndrome ER -