TY - JOUR T1 - Effect on Partial Pressure of Oxygen in Arterial Blood in Percutaneous Vertebroplasty JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 567 LP - 569 VL - 28 IS - 3 AU - A. Uemura AU - Y. Numaguchi AU - M. Matsusako AU - N. Kobayashi AU - Y. Saida AU - M. Rahman Y1 - 2007/03/01 UR - http://www.ajnr.org/content/28/3/567.abstract N2 - BACKGROUND AND PURPOSE: The purpose of this study is to estimate the change in partial pressure of oxygen (Pao2) during percutaneous vertebroplasty and also to examine the factors related to the change in Pao2.MATERIALS AND METHODS: We retrospectively reviewed preprocedural and postprocedural Pao2 of 59 consecutive patients who underwent percutaneous vertebroplasty between November 2003 and April 2005 (11 men and 48 women; age range, 50–93; mean age, 75 years). Fifty-four patients were treated for osteoporosis-related fractures and 5 had malignant disease. Percutaneous vertebroplasty was performed in a conventional manner under local anesthetics and conscious sedation. Preprocedural and postprocedural blood drawing was performed 5 days to 30 minutes before percutaneous vertebroplasty and also at 30 minutes after the injection of bone cement. The difference between preprocedural and postprocedural data of Pao2 was correlated with patients’ age, number of treated vertebral bodies, presence of cement leakage, and presence of malignant neoplasm for each patient.RESULTS: Mean pre-Pao2 and post-Pao2 were 80.9 ± 1.4 and 70.6 ± 1.3 mm Hg (mean ± SE) respectively (P = .0001). Using analysis of variance, there was a significant difference according to the number of vertebral bodies. There was a positive trend of decrease in Pao2 according to the number of vertebral bodies during percutaneous vertebroplasty. Using multiple linear regression and after adjusting by preprocedural Pao2 and other variables, the number of vertebral bodies was still highly significant.CONCLUSION: Pao2 decreases during percutaneous vertebroplasty, and there is a correlation between the number of treated vertebral bodies and decrease in Pao2. ER -