PT - JOURNAL ARTICLE AU - Lange, T. AU - Dydak, U. AU - Roberts, T.P.L. AU - Rowley, H.A. AU - Bjeljac, M. AU - Boesiger, P. TI - Pitfalls in Lactate Measurements at 3T DP - 2006 Apr 01 TA - American Journal of Neuroradiology PG - 895--901 VI - 27 IP - 4 4099 - http://www.ajnr.org/content/27/4/895.short 4100 - http://www.ajnr.org/content/27/4/895.full SO - Am. J. Neuroradiol.2006 Apr 01; 27 AB - SUMMARY: In clinical MR spectroscopy at higher field strengths, lactate may show reduced or absent signal intensity at an echo time of 144 ms. Although this false-negative result may be predicted from theory, experimental verification and clinical impact have not been fully established. Using scanners from 3 major vendors, spectra from phantoms and patients demonstrate the lactate signal loss and potential error in interpretation. Strategies are discussed to overcome, or at least alleviate, this problem.