RT Journal Article SR Electronic T1 Optimizing the Detection of Subtle Insular Lesions on MRI When Insular Epilepsy Is Suspected JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1581 OP 1585 DO 10.3174/ajnr.A6143 VO 40 IS 9 A1 J. Blustajn A1 S. Krystal A1 D. Taussig A1 S. Ferrand-Sorbets A1 G. Dorfmüller A1 M. Fohlen YR 2019 UL http://www.ajnr.org/content/40/9/1581.abstract AB SUMMARY: Insular epilepsy is underdiagnosed and accounts for a number of failed operations. Identifying insular target lesions on MR imaging can help guide intracranial electroencephalography and improve the outcome of surgery. In this study, we present a novel method of exploring the insular region for subtle lesions on 3D MR imaging by MPR postprocessing of slices in oblique reference planes. Using this method, we retrospectively reviewed presurgical MRIs that were initially considered to have normal findings in 7 pediatric patients with intractable insular epilepsy. Insular epilepsy was confirmed in these patients on stereo-electroencephalography and histopathology. The MPR postprocessing method we describe helped detect subtle insular lesions in all 7 patients.FCDfocal cortical dysplasiaSEEGstereo-electroencephalography