RT Journal Article SR Electronic T1 Improved Visibility of the Subthalamic Nucleus on High-Resolution Stereotactic MR Imaging by Added Susceptibility (T2*) Contrast Using Multiple Gradient Echoes JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1093 OP 1094 DO 10.3174/ajnr.A0527 VO 28 IS 6 A1 E. Elolf A1 V. Bockermann A1 T. Gringel A1 M. Knauth A1 P. Dechent A1 G. Helms YR 2007 UL http://www.ajnr.org/content/28/6/1093.abstract AB SUMMARY: Reliable identification of the subthalamic nucleus (STN) is a critical step in deep brain stimulation for Parkinson disease but difficult on T1-weighted stereotactic MR imaging. By simultaneous imaging of multiple gradient echoes, susceptibility contrast is added to conventional T1-weighted high-resolution MR image. Thus, the visibility of the STN is enhanced on a second co-localized dataset by exploiting the sensitivity of the T2*-relaxation to local iron deposits. The feasibility is underpinned by quantitative measurements on healthy adults.