PT  - JOURNAL ARTICLE
AU  - D.G. Corrêa
AU  - T. A. L. Freddi
AU  - H. Werner
AU  - F.P.P.L. Lopes
AU  - M.E.L. Moreira
AU  - F.C.P. de Almeida Di Maio Ferreira
AU  - J.M. de Andrade Lopes
AU  - F.C. Rueda-Lopes
AU  - L.C.H. da Cruz, Jr
TI  - Brain MR Imaging of Patients with Perinatal Chikungunya Virus Infection
AID  - 10.3174/ajnr.A6339
DP  - 2020 Jan 01
TA  - American Journal of Neuroradiology
PG  - 174--177
VI  - 41
IP  - 1
4099  - http://www.ajnr.org/content/41/1/174.short
4100  - http://www.ajnr.org/content/41/1/174.full
SO  - Am. J. Neuroradiol.2020 Jan 01; 41
AB  - SUMMARY: Since 2005, it has been known that mother-to-child transmission of the chikungunya virus is possible. Transmission generally occurs in the perinatal period. In the present study, we describe the brain lesions seen on MR imaging of 6 cases of perinatal chikungunya infection. Patients who underwent brain MR imaging in the acute phase presented with areas of restricted diffusion in the white matter, suggesting a perivascular distribution, whereas those in the subacute/late phase showed cystic lesions, also with a perivascular distribution, with or without brain atrophy. One patient also presented with scattered hemorrhages in the frontal and parietal lobes. Important differential diagnoses include rotavirus, Parechovirus, herpes simplex infection, and hypoxic-ischemic encephalopathy, depending on the disease phase.CHIKVchikungunya virusIgMimmunoglobulin MRT-PCRreverse transcription–polymerase chain reaction