TY - JOUR T1 - Theoretic Basis and Technical Implementations of CT Perfusion in Acute Ischemic Stroke, Part 2: Technical Implementations JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 885 LP - 892 DO - 10.3174/ajnr.A1492 VL - 30 IS - 5 AU - A.A. Konstas AU - G.V. Goldmakher AU - T.-Y. Lee AU - M.H. Lev Y1 - 2009/05/01 UR - http://www.ajnr.org/content/30/5/885.abstract N2 - SUMMARY: CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct “core”) and the severely ischemic but potentially salvageable tissue (“penumbra”). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time. ER -