RT Journal Article
SR Electronic
T1 COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1384
OP 1387
DO 10.3174/ajnr.A6651
VO 41
IS 8
A1 R. Hanafi
A1 P.-A. Roger
A1 B. Perin
A1 G. Kuchcinski
A1 N. Deleval
A1 F. Dallery
A1 D. Michel
A1 L. Hacein-Bey
A1 J.-P. Pruvo
A1 O. Outteryck
A1 J.-M. Constans
YR 2020
UL http://www.ajnr.org/content/41/8/1384.abstract
AB SUMMARY: Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of “endotheliitis” associated with this novel coronavirus.ACE2angiotensin converting enzyme 2COVID-19coronavirus disease 2019SARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2