TY - JOUR T1 - COVID-19-Associated Cytotoxic Lesions of the Corpus Callosum JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. DO - 10.3174/ajnr.A6713 AU - P. Gaur AU - L. Dixon AU - B. Jones AU - H. Lyall AU - W. Jan Y1 - 2020/08/20 UR - http://www.ajnr.org/content/early/2020/08/20/ajnr.A6713.abstract N2 - SUMMARY: There are very limited published data on the neurologic complications associated with coronavirus disease 2019 (COVID-19) in the pediatric population. Here we present the first 2 pediatric cases of presumed COVID-19 related cytotoxic lesions of the corpus callosum. Similar to reports in adults, these cases suggest that the COVID-19 infection in children may rarely mediate a hyperinflammatory response that can cause CNS pathology. As the pandemic continues further, the presentation of cytotoxic lesions of the corpus callosum should prompt radiologists to consider COVID-19, among other known causes.CLOCCcytotoxic lesions of the corpus callosumCOVID-19coronavirus disease 2019CRPC-reactive proteinRT-PCRreal-time reverse transcriptase polymerase chain reactionSARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2 ER -