TY - JOUR T1 - Brain Tumor Imaging in Clinical Trials JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 419 LP - 424 DO - 10.3174/ajnr.A0963 VL - 29 IS - 3 AU - J.W. Henson AU - S. Ulmer AU - G.J. Harris Y1 - 2008/03/01 UR - http://www.ajnr.org/content/29/3/419.abstract N2 - SUMMARY: There are substantial challenges in the radiologic evaluation of tumor size during clinical trials, and it is important for neuroradiologists to have a firm understanding of these issues. This review will examine measurement approaches, response criteria, selection of lesions for measurement, technical imaging considerations, interval between tumor measurements and response confirmation, and validity of imaging as a measure of efficacy. ER -