PT  - JOURNAL ARTICLE
AU  - E. Zvi
AU  - A. Shemer
AU  - S. toussia-Cohen
AU  - D. Zvi
AU  - Y. Bashan
AU  - L. Hirschfeld-dicker
AU  - N. Oselka
AU  - M.-M. Amitai
AU  - O. Ezra
AU  - O. Bar-Yosef
AU  - E. Katorza
TI  - Fetal Exposure to MR Imaging: Long-Term Neurodevelopmental Outcome
AID  - 10.3174/ajnr.A6771
DP  - 2020 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1989--1992
VI  - 41
IP  - 11
4099  - http://www.ajnr.org/content/41/11/1989.short
4100  - http://www.ajnr.org/content/41/11/1989.full
SO  - Am. J. Neuroradiol.2020 Nov 01; 41
AB  - BACKGROUND AND PURPOSE: Very few studies have investigated long-term neurodevelopment of children exposed to MR imaging antenatally. Thus, the purpose of our study was to evaluate long-term neurodevelopmental outcomes of children exposed to MR imaging during pregnancy.MATERIALS AND METHODS: We conducted a historical prospective cohort study in a single tertiary medical center. Women exposed to 1.5T noncontrast MR imaging for maternal or fetal indications were matched to unexposed controls. Long-term neurodevelopmental outcomes were evaluated of their children, 2.5 to 6 years of age, according to the Vineland-II Adaptive Behavior Scale. The Vineland-II Adaptive Behavior Scale assesses communication, daily living skills, socialization, and motor skills. A composite score summarizes these 4 domains.RESULTS: A total of 131 exposed women matched our inclusion criteria and were included in the study group, and 771 unexposed women, in the control group. No difference was identified in the Vineland-II Adaptive Behavior Scale composite score between the children of the study and control groups (mean, 110.79 versus 108.18; P = .098). Differences were also not observed between the children of the 2 groups in 3 of the 4 questionnaire domains: communication (108.84 versus 109.10; P = .888), daily living skills (109.51 versus 108.28; P = .437), and motor skills (105.09 versus 104.42; P = .642). However, the socialization score was favorable for the study group (112.98 versus 106.47; P < .001).CONCLUSIONS: Exposure to 1.5T noncontrast MR imaging during pregnancy had no harmful effects on long-term neurodevelopmental outcomes. This study contributes to understanding the safety of MR imaging during pregnancy.VABSVineland-II Adaptive Behavior Scale