PT  - JOURNAL ARTICLE
AU  - Emblem, K.E.
AU  - Bjornerud, A.
TI  - An Automatic Procedure for Normalization of Cerebral Blood Volume Maps in Dynamic Susceptibility Contrast−Based Glioma Imaging
AID  - 10.3174/ajnr.A1680
DP  - 2009 Nov 01
TA  - American Journal of Neuroradiology
PG  - 1929--1932
VI  - 30
IP  - 10
4099  - http://www.ajnr.org/content/30/10/1929.short
4100  - http://www.ajnr.org/content/30/10/1929.full
SO  - Am. J. Neuroradiol.2009 Nov 01; 30
AB  - SUMMARY: To characterize gliomas from dynamic susceptibility contrast (DSC)–based cerebral blood volume (CBV) maps, a CBV value from a normal-appearing region of interest is typically identified manually and used to normalize the CBV maps. This method is user-dependent and time-consuming. We propose an alternative approach based on automatic identification of normal-appearing first-pass curves from brain tissue. Our results in 101 patients suggest similar or better diagnostic accuracy values than the manual approach.