TY - JOUR T1 - Safety Profile of Infinity Deep Brain Stimulation Electrode Placement in a 1.5T Interventional MRI Suite: Consecutive Single-Institution Case Series JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 2257 LP - 2262 DO - 10.3174/ajnr.A6776 VL - 41 IS - 12 AU - N. Gravbrot AU - M. Saranathan AU - L.M. Nagae AU - J. Becker AU - W.S. Kasoff Y1 - 2020/12/01 UR - http://www.ajnr.org/content/41/12/2257.abstract N2 - SUMMARY: “Asleep” deep brain stimulation using general anesthesia and intraoperative MR imaging guidance is considered “off-label” use by current FDA guidelines but is widely used in neurosurgical practice, and excellent safety has been demonstrated using first-generation, omnidirectional electrodes. Safety data for second-generation, directional electrodes in the interventional MR imaging environment have not yet been published. Herein, we report 34 cases of asleep deep brain stimulation using second-generation, directional electrodes in an interventional MR imaging suite at a single institution. Procedural complications and imaging data are described. All patients underwent postoperative MR imaging with fully implanted (“internalized”) electrodes after scalp closure; 4 patients also underwent MR imaging with “externalized” electrodes before scalp closure. No MR imaging–related complications were observed, and procedural complication rates were comparable to prior series. This suggests that the use of second-generation, directional electrodes in the interventional MR imaging environment appears to be safe when following manufacturer-published imaging guidelines.DBSdeep brain stimulationETessential tremorGPiglobus pallidus internusiMRIinterventional MRIPDParkinson diseaseSARspecific absorption rateSTNsubthalamic nucleusWMnwhite matter-nulledVimventralis intermedius ER -