PT  - JOURNAL ARTICLE
AU  - Ogawa, T
AU  - Inugami, A
AU  - Hatazawa, J
AU  - Kanno, I
AU  - Murakami, M
AU  - Yasui, N
AU  - Mineura, K
AU  - Uemura, K
TI  - Clinical positron emission tomography for brain tumors: comparison of fludeoxyglucose F 18 and L-methyl-11C-methionine.
DP  - 1996 Feb 01
TA  - American Journal of Neuroradiology
PG  - 345--353
VI  - 17
IP  - 2
4099  - http://www.ajnr.org/content/17/2/345.short
4100  - http://www.ajnr.org/content/17/2/345.full
SO  - Am. J. Neuroradiol.1996 Feb 01; 17
AB  - PURPOSE To evaluate the differences between fludeoxyglucose F 18 (FDG) and L-methyl-11C-methionine (11C-methionine) as tracers for positron emission tomography (PET) in the evaluation of brain tumors.METHODS We analyzed 10 patients with histologically verified cerebral glioma or meningioma and 1 patient with a neuroradiologic diagnosis of low-grade glioma by using FDG, 11C-methionine, and PET. We qualitatively and quantitatively evaluated the extent and degree of accumulation of FDG and 11C-methionine in the tumor tissue.RESULTS Although PET with FDG depicted malignant tumors as a hot spot in all cases, it was not able to delineate the extent of the tumor. Conversely, PET with 11C-methionine outlined the tumors as areas of increased accumulation of 11C-methionine, regardless of the degree of malignancy.CONCLUSION PET with FDG and with 11C-methionine can play complementary roles in the evaluation of brain tumors.