RT Journal Article SR Electronic T1 Clinical positron emission tomography for brain tumors: comparison of fludeoxyglucose F 18 and L-methyl-11C-methionine. JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 345 OP 353 VO 17 IS 2 A1 T Ogawa A1 A Inugami A1 J Hatazawa A1 I Kanno A1 M Murakami A1 N Yasui A1 K Mineura A1 K Uemura YR 1996 UL http://www.ajnr.org/content/17/2/345.abstract AB PURPOSE To evaluate the differences between fludeoxyglucose F 18 (FDG) and L-methyl-11C-methionine (11C-methionine) as tracers for positron emission tomography (PET) in the evaluation of brain tumors.METHODS We analyzed 10 patients with histologically verified cerebral glioma or meningioma and 1 patient with a neuroradiologic diagnosis of low-grade glioma by using FDG, 11C-methionine, and PET. We qualitatively and quantitatively evaluated the extent and degree of accumulation of FDG and 11C-methionine in the tumor tissue.RESULTS Although PET with FDG depicted malignant tumors as a hot spot in all cases, it was not able to delineate the extent of the tumor. Conversely, PET with 11C-methionine outlined the tumors as areas of increased accumulation of 11C-methionine, regardless of the degree of malignancy.CONCLUSION PET with FDG and with 11C-methionine can play complementary roles in the evaluation of brain tumors.