PT  - JOURNAL ARTICLE
AU  - J M Eskridge
AU  - W McAuliffe
AU  - B Harris
AU  - D K Kim
AU  - J Scott
AU  - H R Winn
TI  - Preoperative endovascular embolization of craniospinal hemangioblastomas.
DP  - 1996 Mar 01
TA  - American Journal of Neuroradiology
PG  - 525--531
VI  - 17
IP  - 3
4099  - http://www.ajnr.org/content/17/3/525.short
4100  - http://www.ajnr.org/content/17/3/525.full
SO  - Am. J. Neuroradiol.1996 Mar 01; 17
AB  - PURPOSE To determine whether hemangioblastomas, highly vascular tumors requiring surgery that is potentially complicated by excessive bleeding, can be embolized safely by using interventional techniques that furnish a more avascular surgical field.METHODS Nine hemangioblastomas involving either the cerebellum or the spinal cord were embolized preoperatively. In each case the feeding artery was selectively catheterized with a microcatheter and the hypervascular tumor nidus was devascularized with polyvinyl alcohol particles.RESULTS Two patients who had undergone recent attempts as surgical resection at another institution had repeat surgery after endovascular embolization rendered the tumor nidus avascular. At surgery, the tumor was completely removed in one case and markedly debulked in the other. In all nine cases, blood loss after embolization was reported to be less than expected by experienced surgeons. In addition, manipulation and removal of the tumor was reported to be subjectively easier in these embolized tumors. The embolization procedure caused no permanent complications; however, one patient with a posterior fossa hemangioblastoma and hydrocephalus worsened clinically within 12 hours of embolization. This event was thought to be caused by obstructive hydrocephalus resulting from tumor swelling. Emergency craniotomy, ventricular decompression, and surgical resection of the tumor produced complete resolution of the signs and symptoms.CONCLUSIONS Our results indicate that preoperative embolization of hemangioblastomas is a safe procedure that is useful in aiding surgical resection of these highly vascular tumors.