TY - JOUR T1 - Endovascular Treatment of Ruptured Intracranial Blister Aneurysms: A Systematic Review and Meta-analysis JF - American Journal of Neuroradiology JO - Am. J. Neuroradiol. SP - 538 LP - 545 DO - 10.3174/ajnr.A6924 VL - 42 IS - 3 AU - A. Scerrati AU - J. Visani AU - M.E. Flacco AU - L. Ricciardi AU - S. Trungu AU - A. Raco AU - F. Dones AU - P. De Bonis AU - C.L. Sturiale Y1 - 2021/03/01 UR - http://www.ajnr.org/content/42/3/538.abstract N2 - BACKGROUND: Endovascular treatment of blister aneurysms is a promising approach, even though they are vascular lesions challenging to treat due to their angioarchitectural characteristics.PURPOSE: Our aim was to investigate clinical and radiologic outcomes after endovascular treatment of ruptured blister aneurysms.DATA SOURCES: PubMed, Ovid MEDLINE, Ovid EMBASE, Scopus, and the Web of Science were screened.STUDY SELECTION: We performed a comprehensive review of the literature from 2010 to 2019 reporting series of patients with blister aneurysms treated with an endovascular approach.DATA ANALYSIS: Event rates were pooled across studies using a random effects meta-analysis.DATA SYNTHESIS: A total of 32 studies reporting on 684 patients (707 aneurysms) were included. Stent placement, stent-assisted coiling, and flow diversion were the most commonly described treatments (282, 256, and 155 patients, respectively). The long-term complete occlusion rate was 76.9% (95% CI, 69.2%–83.9%). The perioperative complication rate was 8.9%, and clinical outcome at final follow-up was mRS <2 in 76.6% (95% CI, 68.2%–84.2%) of patients. The mortality rate was 4.7% (95% CI, 2.30%–7.80%). Among the different techniques, stent-assisted coiling is the one that had the higher rate of immediate occlusion (63.4%); however, the occlusion rate at the final follow-up was comparable among the different techniques.LIMITATIONS: Different techniques were described and data were reported in a nonhomogeneous way, possibly representing a bias in the present study.CONCLUSIONS: This study suggests that endovascular treatment of blister aneurysms is associated with good long-term occlusion rates and reasonable complication and mortality rates. There is no consensus on the best endovascular techniques in blister aneurysm management.HHHunt and Hess ER -