RT Journal Article
SR Electronic
T1 Velocity Measurements in the Middle Cerebral Arteries of Healthy Volunteers Using 3D Radial Phase-Contrast HYPRFlow: Comparison with Transcranial Doppler Sonography and 2D Phase-Contrast MR Imaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 54
OP 59
DO 10.3174/ajnr.A2240
VO 32
IS 1
A1 W. Chang
A1 B. Landgraf
A1 K.M. Johnson
A1 S. Kecskemeti
A1 Y. Wu
A1 J. Velikina
A1 H. Rowley
A1 O. Wieben
A1 C. Mistretta
A1 P. Turski
YR 2011
UL http://www.ajnr.org/content/32/1/54.abstract
AB BACKGROUND AND PURPOSE: We have developed PC HYPRFlow, a comprehensive MRA technique that includes a whole-brain CE dynamic series followed by PC velocity-encoding, yielding a time series of high-resolution morphologic angiograms with associated velocity information. In this study, we present velocity data acquired by using the PC component of PC HYPRFlow (PC-VIPR). MATERIALS AND METHODS: Ten healthy volunteers (6 women, 4 men) were scanned by using PC HYPRFlow and 2D-PC imaging, immediately followed by velocity measurements by using TCD. Velocity measurements were made in the M1 segments of the MCAs from the PC-VIPR, 2D-PC, and TCD examinations. RESULTS: PC-VIPR showed approximately 30% lower mean velocity compared with TCD, consistent with other comparisons of TCD with PC-MRA. The correlation with TCD was r = 0.793, and the correlation of PC-VIPR with 2D-PC was r = 0.723. CONCLUSIONS: PC-VIPR is a technique capable of acquiring high-resolution MRA of diagnostic quality with velocity data comparable with TCD and 2D-PC. The combination of velocity information and fast high-resolution whole-brain morphologic angiograms makes PC HYPRFlow an attractive alternative to current MRA methods. CEcontrast-enhancedCE-VIPRcontrast-enhanced vastly undersampled isotropic projection reconstruction2D-PC2D phase-contrastHYPR-LRhighly constrained local projection reconstructionMCAmiddle cerebral arteryMRAMR angiographyPCphase-contrastPC HYPRFlowtime-resolved MRA using highly constrained projection reconstruction and PC-VIPR data for the reconstruction convolutionPC-MRAphase-contrast MR angiographyPC-VIPRphase-contrast vastly undersampled isotropic projection reconstructionSNRsignal intensity–to-noise ratioTCDtranscranial Doppler sonographyVENCvelocity encodingWSSwall shear stress