RT Journal Article
SR Electronic
T1 Corpus Callosum Length by Gestational Age as Evaluated by Fetal MR Imaging
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 490
OP 494
DO 10.3174/ajnr.A2310
VO 32
IS 3
A1 J.H. Harreld
A1 R. Bhore
A1 D.P. Chason
A1 D.M. Twickler
YR 2011
UL http://www.ajnr.org/content/32/3/490.abstract
AB SUMMARY: Although suspected corpus callosum abnormality is a common indication for fetal MR imaging, biometric data specific to MR imaging are sparse. We sought to characterize growth in corpus callosum length by EGA with fetal MR imaging. Corpus callosum segments were assessed and overall corpus callosum length was measured and plotted against the EGA for 68 anatomically normal fetal brains ranging in EGA from 18.5 to 37.7 weeks, and linear and polynomial regression models were calculated. The body of the corpus callosum was identified in all fetuses, followed in frequency by the splenium (91.2%), genu (85.3%), and rostrum (32.4%). Measurements of corpus callosum length by MR imaging were in agreement with values established by sonography. A second-degree polynomial function was the best fit for callosal length by EGA. Understanding this normal growth pattern may enhance detection of subtle growth abnormalities. adjadjustedCCcorpus callosumCIconfidence intervalCNScentral nervous systemEGAestimated gestational ageHASTEhalf-Fourier acquired single-shot turbo spin-echoSNRsignal-to-noise ratioSSFSEsingle-shot fast spin-echoTEeffeffective echo-time