%0 Journal Article %A R.A. Salgado %A P.G. Jorens %A I. Baar %A P. Cras %A G. Hans %A P.M. Parizel %T Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings %D 2010 %R 10.3174/ajnr.A1889 %J American Journal of Neuroradiology %P 565-566 %V 31 %N 3 %X SUMMARY: We report the clinical, MR imaging, and proton MR spectroscopy findings in a middle-aged woman with proved methadone-induced toxic leukoencephalopathy. The imaging characteristics of this unusual condition have been reported only rarely in the medical literature. We show that the imaging findings in methadone-induced toxic leukoencephalopathy are similar, though not identical, to previously reported cases of neurologic deterioration due to heroin inhalation. ChocholineCrcreatineFLAIRfluid-attenuated inversion recoveryNAAN-acetylaspartate %U https://www.ajnr.org/content/ajnr/31/3/565.full.pdf