RT Journal Article
SR Electronic
T1 Radiologic Evaluation Criteria for Chronic Subdural Hematomas: Recommendations for Clinical Trials
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
DO 10.3174/ajnr.A7503
A1 R. McDonough
A1 M. Bechstein
A1 J. Fiehler
A1 U. Zanolini
A1 H. Rai
A1 A. Siddiqui
A1 E. Shotar
A1 A. Rouchaud
A1 K. Kallmes
A1 M. Goyal
A1 S. Gellissen
YR 2022
UL http://www.ajnr.org/content/early/2022/05/26/ajnr.A7503.abstract
AB SUMMARY: Embolization of the middle meningeal artery has gained substantial interest as a therapy for chronic subdural hematomas. For the results of the currently running chronic subdural hematoma trials to inform clinical practice, sufficient accuracy and matching definitions are necessary. We summarized the current practice in chronic subdural hematoma evaluation and derived suggestions on reporting standards using the {Nested} Knowledge AutoLit living review platform. On the basis of the most commonly reported data elements, we suggested a set of standardized image-based study end points for chronic subdural hematoma evaluation for future trials. The measurement methods and reporting standards as proposed in this article have been derived from published best practices and are endorsed by the European Society of Minimally Invasive Neurological Therapy’s research committee. The standardization of radiologic outcome measures and measurement techniques in chronic subdural hematoma embolization trials would increase the impact and implication of each trial as well as facilitate data pooling for increased statistical power and, therefore, translation to clinical practice.cSDHchronic subdural hematomaMLSmidline-shiftMLS-MMLS versus midline or displacement perpendicular to the midlineMLS-TMLS transverseMMAmiddle meningeal arteryNK{Nested} KnowledgeSDHsubdural hematoma