PT - JOURNAL ARTICLE AU - O. Esnault AU - A. Rouxel AU - E. Le Nestour AU - G. Gheron AU - L. Leenhardt TI - Minimally Invasive Ablation of a Toxic Thyroid Nodule by High-Intensity Focused Ultrasound AID - 10.3174/ajnr.A1979 DP - 2010 Nov 01 TA - American Journal of Neuroradiology PG - 1967--1968 VI - 31 IP - 10 4099 - http://www.ajnr.org/content/31/10/1967.short 4100 - http://www.ajnr.org/content/31/10/1967.full SO - Am. J. Neuroradiol.2010 Nov 01; 31 AB - SUMMARY: HIFU is used in the treatment of cancer (prostate, breast) and uterine fibroma but not yet in TNs. This case report describes the first successful ablation of a toxic TN with HIFU. TSH and radioiodine scan normalization were achieved without complications and maintained for 18 months. HIFU treatment is a minimally invasive technique that may be an effective safe alternative to radioiodine or surgery in patients with toxic TNs. AFTNautonomously functioning thyroid noduleENTears, nose, and throatFT3triiodothyronine, freeFT4thyroxine, freeHIFUhigh-intensity focused ultrasound123Iiodine 123TNthyroid noduleTSHthyroid-stimulating hormone, thyrotropin