RT Journal Article SR Electronic T1 Minimally Invasive Ablation of a Toxic Thyroid Nodule by High-Intensity Focused Ultrasound JF American Journal of Neuroradiology JO Am. J. Neuroradiol. FD American Society of Neuroradiology SP 1967 OP 1968 DO 10.3174/ajnr.A1979 VO 31 IS 10 A1 O. Esnault A1 A. Rouxel A1 E. Le Nestour A1 G. Gheron A1 L. Leenhardt YR 2010 UL http://www.ajnr.org/content/31/10/1967.abstract AB SUMMARY: HIFU is used in the treatment of cancer (prostate, breast) and uterine fibroma but not yet in TNs. This case report describes the first successful ablation of a toxic TN with HIFU. TSH and radioiodine scan normalization were achieved without complications and maintained for 18 months. HIFU treatment is a minimally invasive technique that may be an effective safe alternative to radioiodine or surgery in patients with toxic TNs. AFTNautonomously functioning thyroid noduleENTears, nose, and throatFT3triiodothyronine, freeFT4thyroxine, freeHIFUhigh-intensity focused ultrasound123Iiodine 123TNthyroid noduleTSHthyroid-stimulating hormone, thyrotropin